"Higher Ammo Max"

Increases max ammo capacity for shells, energy, bolts and explosives from 55 to 99.
Increases max ammo capacity for bullets from 255 to 555.

Ammo drops are dependent on the percent of ammunition held, so being out of ammo will lead to pickups being more frequent than if back muscle is not being run.

"Some Kills Regenerate HP"

Any time an enemy is killed they have a 1 in 13 (7.69%) chance of healing the player 1 HP, applied automatically.
Regardless of current HP this will always have the same chance to heal which differs from HP drops.

Any time an enemy is killed they have a 1 in 13(7.69%) chance of giving the player 1 HP applied automatically. While health drops are effected by current health, Bloodlust procs are not. This means that it can proc even if HP is full, to no additional benefit.

"No Damage From Explosions And Fire When Under 4 HP"
(Poor flavor text, it's at or below 4 HP.)

Any explosive or fire damage taken will not set the player below 4 HP, regardless of current max HP. It is impossible to die to these damage sources.

Character, enemy and prop damage sources are all included in this so long as they use explosives or fire. It does NOT protect from self-damaging blood weapons, or shielder deflected blood explosions.

Explosives usually deal damage twice in quick succession, but Boiling Veins will prevent the additional hit during the hurt animation.
In layman terms this means that explosives will only do half damage from the full blast of an explosion while above 4 HP.

"Homing Bolts"

• Normal bolts: If passing by an enemy it can adjust slightly to instead pass through that enemy. It will retain the same trajectory if the enemy pierced.
• Large bolts: Similar to normal bolts but with much weaker homing.
• Splinters: Can adjust to a nearby enemy to hit them instead.
• Seekers: Larger homing radius to lock on targets sooner and will take sharper turns to better ensure hits.
• Discs: Will bend towards nearby enemies and will decrease its speed while passing through which can cause extra hits.

"Better Accuracy"

Normal characters: Default accuracy 1, increased to 0.3.
Steroids: Accuracy 1.8, increased to 0.54.
Skeleton: Accuracy 1.5, increased to 0.45.

"Slower Enemy Bullets"

Any projectiles shot by enemies now go 20% slower. Does not effect enemy speed in any way.
Shields deflecting projectiles are not slowed, neither are some non-projectile attacks such as lasers.

"More Speed, Walk Normal On All Terrain"

Adds 0.5 to the total speed.
Floor hazards will no longer effect the player, being cobwebs and ice flooring.

Mutants default speed is 4, bringing it to 4.5.
Plant's speed is 4.5, bringing it to 5.
Skeleton's speed is 3, bringing it to 3.5.
Big Dog's speed is 2, bringing it to 2.5.

(These are the default values but characters constantly move slower due to friction, this is just the best simplification of it.

"Enemies Touching You Take Damage"

Contact damage can now be done to enemies, at 6 damage a tick.
Enemies that deal contact damage will still hurt the player if not killed by gamma guts.
Standing still does 1 tick of damage at a time, meaning that contact damage enemies at 6 HP or below can safely be killed.
Meanwhile moving does 2 ticks of damage at a time, meaning that contact damage enemies at 12 HP or below can safely be killed.
It is recommended to constantly be moving while using this mutation on enemies.

Props are unaffected by gamma guts, as well as vans.

Enemies dying to gamma guts will cause a small shock around the player that does 8 additional damage to any enemies in the immediate vicinity.

"Push Through A Limited Number Of Walls"

Pushing into any wall tile will destroy it.
20 wall tiles may be broken a level, the counter resets to 20 any time a new portal is entered.

A noticeable visual effect will appear when standing next to walls signifying that Hammerhead can be used.
Once all 20 tiles are used up, an audio cue will play to signify it can no longer be used that level.

"Corpses Fly & Hit Harder"

Killing enemies will make their corpses fly substantially farther than their default distance.
Corpse damage is doubled, dealing 2 instead of 1.

"Energy Weapons Deal More Damage"

Any weapon that uses energy ammo will deal additional damage. Each weapon laser type differs from each other, so 'additional damage' is rarely a flat percentage increase but rather higher damage potential.

"More Melee Range"

Any weapon that is a melee gains "more range", even those that use ammo.
In actuality melee shots start further out from the player and are pushed forward at a higher velocity, covering more ground before it disappears.
This leaves a slight blind spot immediately around the player.

Standing behind a wall will reduce melee range while running this mutation.
(Hugging a one wall tile will not effect Jackhammer as its projectile is simply moved forward with some slightly better range)

"Some Kills Regenerate Ammo"

Any time an enemy is killed they have a 2 in 17(11.76%) chance of giving the player 1 ammo drops worth applied automatically.

The ammo given can be any of the 5 ammo types at random regardless of held weapons.

"Extra Chest Spawn"

Every level will include an additional chest. This is chosen randomly between a weapon chest, ammo chest and rad can, which includes any of their special variations.

Skipping 2 weapon chests in the same level counts as +50% towards spawning a big weapon chest, but there cannot be two big weapon chests at a time.
Open Mind will never produce two health chests in a level.
Skipping 2 rad cans in the same level will spawn a Hostile Horror on the next. Only one overflowing rad can will convert into a Hostile Horror in a run.

"Attract Drops And Rads From Further"

Substantially increases the pickup range for drops.
Ammo & HP drops can be reached from much further away, as just walking near a pickup will attract it.
Rads meanwhile are dragged in from the majority of the screen, meaning that just walking in the general direction of rads is enough to collect them.

"More HP And Ammo Drops"

"Most Hit Bullets Become Ammo"

Any weapon that uses bullet ammo will give a 60% chance of returning that ammo to the player automatically, if the bullet makes contact with any prop or enemy.
Bullet weapons that use 1 ammo returns the 1, while bullet weapons that use 2 ammo will return 2 ammo instead.
Incinerator, Pop Gun & Pop Rifle are not effected by this mutation, instead being effected by Shotgun Shoulders. Every other weapon works as intended.

"+4 Max HP"

Increases the player's maximum HP by 4.
This automatically heals for the 4 new HP as well upon entering the next level.

"Less Enemy HP"

Every enemy will have 20% of their max HP removed permanently.
his is always rounded to the nearest whole number.
Bosses and vans are included in this pool.
Any enemy that spawns midway through a level also has the reduced HP, such as IDPD.
Props are not effected by this.

"More HP From Medkits"

Health drops give an additional 2 HP, for a total of +4 HP per drop.
This also effects health chests, which gives a total of +8 HP instead of the usual +4.

"Damage Taken Is Dealt To All Enemies On Screen"

Any damage taken will be returned to all enemies on screen at 2.5x for damage taken.
This is not rounded; enemies will take the exact amount which can leave their health in the decimal points.
If taking more damage than health(losing spirit or going headless as Chicken), it will not deal additional damage; only the actual HP lost.
Similarly taking 0 damage at a time will not proc sharp teeth, such as boiling veins going into effect while at low HP.

"Shells Bounce Further"

Any weapon that uses shells will have the shells bounce back aggressively when in contact with a wall, traveling much further.
Shell weapons at point blank deals extra damage; this mutation also adds that damage to the moment shells bounce off walls, though just for two frames.

Flame weapons do not bounce normally; this lets them bounce once for a short distance.
Incinerator, Pop Gun & Pop Rifle are all effected by this mutation despite being bullet weapons.

"Higher Rate Of Fire As HP Gets Lower"

Additional fire rate is given based on health lost.
The rate is percentage based, so the higher the max health the better the fire rate when low on HP.
Fire rate increase is Current HP / Max HP, for instance being at 50% health puts the players fire rate at 150%.

"Prevents Death Once Recharges At Full HP In The Next Area"

Any hit that would be lethal towards the player will instead be blocked by Strong Spirit, leaving the player at 1 HP instead. Until Spirit is regained any lethal hit will then kill the player.
In actual numbers, a lethal hit consuming Spirit will give about 5 frames of invulnerability. Where there are some damage sources that ignore iframes, this can prevent those from an insta-kill.

In order to regain Strong Spirit, the level Spirit was lost on must be completed. Upon reaching full HP at any following level, Spirit will be recharged and will be there to protect the player once again.
If max HP is at 1 (Chicken/Melting) than Strong Spirit can only ever be used once. It will never recharge unless if max HP is 2 or above.

"Upgrades Your Special Ability"

Thronebutt will enhance each characters specific active ability. In-depth tech on these can be found on their respective character tech pages. A shortened version is as follows:

• Fish: "Water Boost"
• Gives infinite roll with more control.
• Crystal: "Teleportation; Shorter Shielding"
• Eyes: "Stronger Telekinesis"
• Melting: "Bigger Corpse Explosions"
• Plant: "Snare Finishes Enemies Under 33% HP"
• YV: "BRRRAP"
• Pop Pop effect is doubled.
• Steroids: "Firing Gives Ammo For Your Other Weapon; More Effective When Firing Both"
• Robot: "Better Weapon Nutrition"
• Eating ammo gives an additional drop.
• Chicken: "Throws Pierce Through Enemies"
• Rebel: "Higher Ally Rate Of Fire"
• Horror: "Beam Charges Up Faster; Prolonged Beam Use Heals You"
• Rogue: "Stronger Portal Strike"
• Skeleton: "Better Odds"
• Blood Gamble is less likely to injure Skeleton.
• Frog: "Toxic Gas Spreads Faster"
• Big Dog: "Faster Missile And Bullets"

"Kills Lower Your Reload Time"

Any time an enemy is killed 40% of the remaining reload time is removed from both held weapons.

"Mutate Later"

Skips the current set, giving a new set instead after entering the next exit portal.
Patience will not re-appear if taken.

On a vanilla run patience essentially gives a random set, but can be predictable on daily & weekly runs seen here. (link later)

"Get Full HP And Some Ammo"

Last Wish will cure the player back to their max HP.
Gives 20 shells, energy, bolts and explosive ammo, while 200 ammo for bullets.
Held weapons will have the curse debuff removed if applicable.

Additionally functions as a much slower patience, if taken a special flower will spawn on 5-1.
If the flower is fed 4 HP, it will take the player to the secret Jungle area.
Last Wish will be consumed, and a new mutation set will appear.
Last Wish will be re-added to the mutation pool, as rerolls can be done again in loop.

"More Weapon Drops"

Heavy Heart is a secret mutation that will only appear if 3 of the 6 weapon-specific mutations are taken in a run.
These include: Boiling Veins, Bolt Marrow, Laser Brain, Long Arms, Recycle Gland, and Shotgun Shoulders.
Guaranteed to be the first mutation slot of the next set seen after the condition is met.

Increases enemies chances of dropping weapons by 210%, more than double.
As it's multiplicative only enemies that already drop weapons(Link Later) are effected, unlike Crown of Guns which adds a flat rate.
(However Heavy Heart & Crown of Guns can be stacked to that effect.)

"Enemies Sometimes Drop Chests"

Fish's Ultra A mutation that has a 20% chance to convert any enemy drop into a chest instead. Ammo drops become ammo chests, weapon drops become weapon chests and health drops become health chests.

"Infinite Ammo The First 7 Seconds After Exiting A Portal"

Fish's Ultra B mutation that makes ammo not be consumed for the first 7 seconds any time a new stage is entered. Weapon cooldowns still apply normally.

"+6 Max HP"

Crystal's Ultra A mutation that gives her an additional 6 max HP. Can be stacked with Rhino Skin making the max total 20 HP.

"Move While Shielded"

Crystal's Ultra B mutation that allows her to freely move during her shield time at a slow speed.

"Telekinesis Holds Your Projectiles"

Eyes' Ultra A mutation that brings any active projectiles he shot back to him by using telekensis, and can be held in place around him or fired out another time.

"Push Nearby Enemies Away When Not Using Telekinesis"

Eyes' Ultra B mutation that pushes enemies away from him for a radius that covers most of the screen while not using his active ability.

"Blow Up Low HP Enemies"

Melting's Ultra A mutation that lets him use his active on alive enemies if they're under 5 HP.

"3 More Mutations Lose Half Of Your HP"

Melting's Ultra B mutation that gives him an additional 3 mutation pools to choose from at the cost of half of his current max HP. Adding extra HP afterwards(Rhino Skin) will not be halved.

On Non-Beta, Detachment will repeat the mutation sets seen on levels 8 & 9 and then give a new set.
On the Betas, it will give three new sets.

"Big Snare"

Plant's Ultra A mutation that adds 5 additional snares that surrounds the main one for a total of 6.

"Enemies Killed On Your Snare Spawn Saplings"

Plant's Ultra B mutation that will spawn sapling allies from enemies killed on snares. They will burst into blood explosions upon contact with an enemy or running out of health, which does additional damage and can erase enemy projectiles.

"Higher Rate Of Fire"

YV's Ultra A mutation that gives him an additional +40% firerate. With his passive this is an overall 60% boost

Grants access to YV's Crib.

"Free Pop Pop Upgrade"

YV's Ultra B mutation that gives an extra pop to his active without costing extra ammo or reload time.

Grants access to YV's Crib.

"Double Weapons From Chests"

Steroids' Ultra A mutation makes weapon chests always drop the same weapon twice, which also means twice the ammo for that weapon type.

"Ammo Chests Contain All Ammo Types"

Steroids' Ultra B mutation makes ammo & present chests now give ammo for all 5 ammo types when opened.

"High Tier Weapons Only
Auto Eat Weapons Left Behind"

Robot's Ultra A mutation removes weapons that appear up to 2-1 in the normal drop pool. This means that 28 weapons are removed from the pool bringing possible weapon drops from 108 down to 80.

Entering the portal will automatically eat any weapon left behind.

"Eating Weapons Can Drop Chests
Auto Eat Weapons Left Behind"

Robot's Ultra B mutation makes any eaten weapon have a ~43% chance of dropping a chest.

Entering the portal will automatically eat any weapon left behind.

"Kills Extend Bleed Time"

Chicken's Ultra A mutation will add 1 second to the headless timer while headless, but will never go above 5 seconds.

"Thrown Weapons Can Teleport Back To Your Secondary Slot"

Chicken's Ultra B mutation that will automatically return a thrown weapon to her secondary slot once it comes to a stop.

"Start A Level With 2 Allies All Allies Have More HP"

Rebel's Ultra A mutation that automatically gives her two allies for free at the start of a new stage, and all allies max health will be at 30 HP instead of 12 HP.

"Double Ally Spawns"

Rebel's Ultra B mutation that lets her summon 2 allies at a time instead of 1, always at the cost of 2 HP.

"Enemies Explode In Radiation On Death"

Horror's Ultra A mutation that makes destroyed enemies/props that drop radiation upon death will also burst into radiation pellets that cause 1 damage to enemies each.

"Portals Appear Earlier"

Horror's Ultra B mutation that will automatically kill every enemy in the level if their combined health totals less than 140 HP.

"Double Rad Capacity"

Horror's Ultra C mutation that increases the ultra rad meter from 600 rads to 1,200 rads, allowing for more rad beam or ultra weapon usage.

"Double Portal Strike Pickups And Capacity"

Rogue's Ultra A mutation that lets her have up to 6 portal strikes at a time. Canisters will give 2 portal strikes instead; 1 is still consumed per. shot.

"Super Blast Armor"

Rogue's Ultra B mutation that when damaged triggers 6 blast explosions around her instead of the usual 3 giving more coverage/range.

"Back In The Flesh"

Skeleton's Ultra A mutation that will transform him back into Melting. He will automatically be put at level ultra and can choose 8 mutations and ultra. (link logic later)

"Fast Reload After Blood Gamble"

Skeleton's Ultra B mutation that will remove 80% of a weapons reload speed when it is blood gambled.

""Rads Can Spawn Toxic Gas"

Frog's Ultra A mutation that gives each dropped rad a chance to spawn a toxic gas cloud.

""Continuously Spawn Toxic Gas"

Frog's Ultra B mutation that will continually have Frog emit gas while walking or using his active.

""Improved Spin Attack"

Big Dog's Ultra A mutation that doubles the amount of bullets he shoots at a time for the same ammo cost.

""Missiles Fire Bullets"

Big Dog's Ultra B mutation that lets his missile attack shoot bullets in front of them, similar to the boss attack on loop.

"HP Pickups Are Shared"

The Ultra A co-op ultra, any health pickup/chest now will apply to both characters.

"Ammo Pickups Are Shared"

The Ultra B co-op ultra, any ammo pickup/chest now will apply to both characters.
Whoever picks up ammo will have the drop chances apply to them, and then that ammo type will also be shared with the player.
However opening an ammo chest will give ammo both specific to each players' primary weapon independent of each other.